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Project Leader(s): 

Dr. Martin Puterman , University of British Columbia

Project team: 
Dr. Dionne Aleman, University of Toronto
Dr. Derek Atkins, University of British Columbia
Dr. John Blake, Dalhousie University
Dr. Michael Carter, University of Toronto
Dr. Armann Ingolfsson, University of Alberta
Dr. Bora Kolfal, University of Alberta
Dr. Wojtek Michalowski, University of Ottawa
Dr. Jonathan Patrick, University of Ottawa
Dr. Maurice Queyranne, University of British Columbia
Pablo Santibáñez, BC Cancer Agency
Dr. Steven Shechter, University of British Columbia
Dr. Vedat Verter, McGill University
Dr. Greg Zaric, University of Western Ontario
Funding period: 
October 1, 2021 - March 31, 2021
Project Leader(s): 

Dr. Fahima Nekka, Université de Montréal

Project team: 
Dr. Jun Li, Universite de Montreal
Dr. Catherine Litalien, Universite de Montreal
Dr. Anne-Laure Lepeyraque, Universite de Montreal
Dr. Pascal Girard, Merck Serono S.A.
Non-academic participants: 
Funding period: 
October 1, 2021 - March 31, 2021

When patients do not use medications as prescribed, the drugs may lose the ability to treat the disease. However, the impact of variations in patient use is not generally studied during clinical trials. By identifying the reasons for patient non-compliance and individual patient modifications, the team will determine the impact that poor compliance or dosing regimen adjustments have on therapeutic failure. A quantitative analysis of this impact will be developed. Initially, the team will focus on oral chemotherapy where concerns about compliance have become an important issue.

Project Leader(s): 

Dr. Jianhong Wu , York University

Project Website: 
Project team: 
Dr. Julien Arino, McMaster University
Dr. Jacques Bélair, Université de Montréal
Dr. Fred Brauer, University of British Columbia
Dr. Troy Day, Queen's University
Dr. Julien Arino, University of Manitoba
Dr. Jacques Beir, Universite de Montreal
Dr. Fred Bauer, University of British Columbia
Dr. Troy Day, Queen’s University
Dr. Michael Li, University of Alberta
Dr. Charmaine Dean, Simon Fraser University
Dr. David N. Fishman, Ontario Public Health Laboratories
Dr. Jane Heffernan, York University
Dr. Kamran Khan, University of Toronto
Dr. Neal Madras, York University
Dr. Seyed M. Mogadas, University of Winnipeg
Dr. Shigui Ruan, Dalhousie University
Dr. Beni M. Sahai, Cadham Provincial Laboratory
Dr. Robert Smith, University of Ottawa
Dr. Lin Wang, University of New Brunswick
Dr. James Watmough, University of New Brunswick
Dr. Glenn Webb, Vanderbilt University
Dr. Hauiping Zhu, York University
Dr. Pauline van den Driessche, University of Victoria
Funding period: 
April 1, 2021 - March 31, 2021

Assembled at the height of the SARS outbreak in 2003, this project develops a variety of modeling templates.

Project Leader(s): 

Dr. Leon Glass, McGill University & Dr. Edward Vigmond , University of Calgary

Project team: 
Dr. Joshua Leon, Dalhousie University
Dr. Stanley Nattel, Institut de Cardiologie de Montreal
Funding period: 
February 25, 2022 - March 31, 2021

Abnormal heart rhythms, or cardiac arrhythmias, can result in significant physical impairment and can lead to an increased risk for serious medical problems such as stroke or even sudden death. This team uses mathematics to further the understanding of cardiac arrhythmias and to develop new methods to predict which patients are at risk for arrhythmias and methods for their control. In the past year systems were developed to analyze changes in the electrical properties of heart tissue.