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Project Leader(s): 

Dr. Anne Condon , University of British Columbia

Project team: 
Dr. Holger H. Hoos, University of British Columbia
Dr. Ming Li, University of Waterloo
Dr. Irmtraud Meyer, University of British Columbia
Dr. S. Cenk Sahinalp, Simon Fraser University
Dr. Ladislav Stacho, Simon Fraser University
Dr. Peter J. Unrau, Simon Fraser University
Dr. Kaizhong Zhang, University of Western Ontario
Funding period: 
April 1, 2021 - March 31, 2021
Project Leader(s): 

Dr. Michael Brudno, University of Toronto

Project team: 
Dr. Quaid Morris, University of Toronto
Dr. Asher Cutter, University of Toronto
Dr. Alan Moses, University of Toronto
Dr. Lucian Ilie, University of Western Ontario
Non-academic participants: 
Funding period: 
1 April 2021 - 31 March 2021

Even as the number of sequenced genomes is growing rapidly, the process of assembling sequencing data into a genome remains exceptionally challenging. The difficulty is due to the fact that current technologies are unable to sequence a whole genome in one pass, relying instead on the shotgun method: the genome is broken into many small segments (reads) whose sequence is then determined. The information about the location of these reads in the genome is lost, and the assembler must put them back together using the information about the overlaps between the reads.

Project Leader(s): 

Dr. Shelley Bull, University of Toronto

Project team: 
Dr. Rafal Kustra, University of Toronto
Dr. David Tritchler, University of Toronto
Dr. Gerarda Darlington, University of Guelph
Dr. Celia Greenwood, University of Toronto
Dr. Kenneth Morgan, McGill University
Dr. Jinko Graham, Simon Fraser University
Dr. Brad McNeney, Simon Fraser University
Dr. J.C. Loredo-Osti, Memorial University of Newfoundland
Dr. Joseph Beyene, University of Toronto
Funding period: 
February 25, 2022 - March 31, 2021

Complex traits, such as susceptibility to diabetes, cancer or tuberculosis, which vary in human and natural populations, are determined by multiple genetic and environmental factors that interact with one another in complicated ways. This interaction depends upon population characteristics as well as characteristics of the individual and the family.