Dr. Adrian Nachman , University of Toronto
Dr. Jack A. Tuszynski , University of Alberta
Project CyberCell Inc.
Technology Innovations, LLC
National Institute for Nanotechnology
Cross Cancer Institute
McBride Career Group
Howard J. Greenwald P.C.
Multimedia Advanced Computational Infrastructure (MACI)
Canadian-European Research Initiative on Nanostructure (CERION)
Dr. Jiri Patera, Université de Montréal
The development of new biomedical imaging techniques has resulted in significantly better tools for doctors and scientists to image humans and animals in-vivo. Technological developments and new types of imagers with more capabilities are revolutionizing the field. Currently, available technologies for brain imaging include Magnetic Resonance Imaging (MRI), functional MRI, Diffuse Optical Tomography (DOT), Electro-Encephalography (EEG) and Magneto-Encephalography.
Improving Genome Annotation, Molecular Structure and Interaction Prediction: An Algorithmic Study of Biomolecular Functions
Dr. Anne Condon , University of British Columbia
Dr. Martin Puterman , University of British Columbia
BC Cancer Agency
Canadian Blood Services
Cancer Care Ontario
Children's Hospital of Eastern Ontario
City of Calgary Public Safety Communications
The Community Care Access Centre
Edmonton Emergency Medical Services
Government of Nova Scotia, Department of Health
Hamilton Health Sciences
Jewish General Hospital
Leaders for Life
Montreal Neurological Institute and Hospital
Ontario Ministry of Health and Long Term Care, Health System Strategy Division
The Ottawa Hospital
Princess Margaret Hospital
Provincial Health Services Authority
Strathcona County Emergency Services
Sunnybrook Health Sciences Centre
Vancouver General Hospital - VGH Surgery
Vancouver Island Health Authority
Dr. Fahima Nekka , Université de Montréal
Dr. Peter Swain , McGill University
Dr. Daniel Coombs, University of British Columbia
Diseases such as diabetes, Alzheimer's, HIV and blood disorders present challenges to our society, our healthcare and our basic scientific understanding of physiological processes within the human body. Mathematical modelling can be used to help scientists decipher the processes at work in these complex diseases at a molecular, cellular and organ level. Recently, research team members examined the ways in which drugs such as Filgrastim could be used to replenish levels of white blood cells, a common challenge following chemotherapy.
Dr. Fahima Nekka, Université de Montréal
When patients do not use medications as prescribed, the drugs may lose the ability to treat the disease. However, the impact of variations in patient use is not generally studied during clinical trials. By identifying the reasons for patient non-compliance and individual patient modifications, the team will determine the impact that poor compliance or dosing regimen adjustments have on therapeutic failure. A quantitative analysis of this impact will be developed. Initially, the team will focus on oral chemotherapy where concerns about compliance have become an important issue.
[url=mailto:firstname.lastname@example.org]Dr. Mads Kaern[/url] , University of Ottawa
The goal of the MITACS-funded research program on reverse-engineering cellular complexity is to develop new mathematical tools and algorithms for analyzing genetic switching networks. Many genes operate as switches and are turned on and off, like light bulbs, when needed. Understanding the regulatory circuits that control this switching behaviour would improve our ability to modulate gene activity, provide clues to fundamental biological design principles, and lead to better synthetic circuits for biotechnological applications.
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