Optimizing Cancer Immunotherapy with the use of Mathematical Models
Postdoctoral fellow: Dr. Raluca Eftimie, Pathology and Molecular Medicine, McMaster University
Lead faculty member: Dr. Jonathan Bramson, Pathology and Molecular Medicine, McMaster University
Cancer emergence and progression are highly complex processes characterized by interactions among a large variety of cells and signalling molecules. It is very difficult to explain these complex interactions through linear thinking and molecular reductionist approaches. Mathematical modeling is a powerful tool that can substantially enhance our capacity for interpreting the data and generate new hypotheses.
Spatio-Temporal Modelling and Mapping of Cancer in Ontario
Postdoctoral fellow: Dr. Paul Nguyen, Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto
Lead faculty member: Dr. Patrick Brown, Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto
This project aims to develop methods and software for performing spatio-temporal analysis of cancer incidence and smoking data in Ontario over long time periods with high spatial resolution. This will allow changes of cancer incidence over time to be better understood, and accommodate rare cancers that require long study periods in order to accumulate data. Because of small counts common to small area analysis, computationally intensive Bayesian inference methods will be needed.
Forest Fires and Spread in Heterogeneous Landscapes
Dr. Thomas Hillen, University of Alberta
