The Inverse Problem Accounting for Therapeutic Variability: Development of a Practical Strategy to Maximally Extract Information from Limited Clinical Data
Postdoctoral fellow: Dr. Olivier Barrière, Faculty of Pharmacy, Université de Montréal
Lead faculty member: Dr. Fahima Nekka, Faculty of Pharmacy, Université de Montréal
Pharmacometrics (PM) is an emerging research area defined as “the science that interprets and describes pharmacology in a quantitative fashion to aid efficient drug development and/or regulatory decision”. Over the years, Dr. Nekka’s team has encompassed deep thinking on how to join and enhance emerging worldwide efforts to make mathematical modeling and simulation a complementary language to the usual empirical and clinical methods used in drug discovery and development. This work is part of these sustained efforts to deal with the complex relationship of dose-exposure-effect of drugs.